$6.16 Billion Per Drug Approval: Almost Half of Big Pharma Companies Hit Negative R&D Productivity

Prof. Oliver Gassmann and fellow researchers have calculated the R&D investments made by big pharma companies to get a new drug approved by the FDA. The result for the period from 2001 to 2020 and the 16 leading research-based pharmaceutical companies is a staggering 6.16 billion USD per approved drug. Alex Zhavoronkov has picked up on the story in Forbes and paints “(…) a concerning picture of massive R&D investment yielding few innovative drugs and limited financial payoffs: